Food Supplements – a white paper by LCG AXIO

The white paper “Food Supplements“ by LGC AXIO, an EU FOOD SAFETY PLATFORM member, explores regulatory gaps in the EU and US markets, emphasizing the need for improved standards, given the ease of access to these products in these regions.

The supplements market is growing rapidly, with a diverse range of active ingredients, degradation products, and contaminants requiring careful safety assessment. Recent scientific research supports the health benefits of dietary supplements—including vitamins, minerals, botanicals, and fatty acids—for aspects like athletic performance, cardiovascular health, weight management, and neurological support.
This trend has significantly fueled the supplements industry; however, concerns over quality and safety are rising.
Issues such as discrepancies between labelled and actual ingredient concentrations and the presence of contaminants highlight the need for rigorous oversight. Recent studies highlight significant regulatory gaps in the EU and US, stressing the need for improved methods to ensure reliable measurement of supplement quality and safety. Botanical supplements, in particular, raise concerns over potential side effects and drug interactions, as they lack the strict standards applied to pharmaceuticals. This variability underscores an opportunity for scientists and regulators to collaborate internationally to enhance public health. To meet the demands of informed consumers, more manufacturers are differentiating themselves through testing in accredited labs and participation in Proficiency Testing (PT) schemes, ensuring quality and compliance.

PT is critical in fostering transparency and accountability, helping quality brands distinguish themselves from those of lower quality. Insights from the LGC AXIO PT team reveal that quality markers and contaminants vary widely across products, presenting technical challenges for manufacturers striving to maintain high standards.